Menumenu
  • Home
  • Systematic review Publications

Systematic review Publications

Systematic review Publications

  • Risk of dipeptidyl-peptidase-4 (DPP-4) inhibitors on site-specific cancer: a systematic review and meta-analysis.Abstract

    BACKGROUND: The long-term impact of DPP-4 inhibition is unknown and there are concerns about the influence of DPP-4 inhibition on carcinogenesis of the pancreas and thyroid. As DPP-4 is a rather unselective enzyme present in many tissues, we focuseon all specific cancer types. METHODS: PubMed and EMBASE were searched between Jan 2005 and Apr 2017 to identify studies comparing DPP-4 inhibitors with either placebo or active drugs on cancer risk

    Overbeek JA, Bakker M, van der Heijden Aawa, van Herk-Sukel MPP, Herings RMC, Nijpels G. Diabetes Metab Res Rev. 2018 Mar 23; 34 e3004.