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  • Effect of reimbursement restriction policy on the use of benzodiazepines in the Netherlands: an interrupted time series analysis.Abstract

    OBJECTIVES: Use of benzodiazepines has health risks. Reimbursement was restricted in the Netherlands from January 2009 onwards with the goal to reduce chronic use and healthcare expenditures. The aim of this study is to assess the initial and long-erm effects of this policy on benzodiazepine use. DESIGN: Interrupted time series analysis, segmented regression models, Kaplan-Meier survival analysis and Cox proportional hazards analysis

    Stoker LJ, Heerdink ER, Janssen R, Egberts TCG. BMJ Open. 2019 Sep 24; 9 e029148.